RNASEL antibody (AA 472-741)

Catalog No. ABIN6146994

This anti-RNASEL antibody is a Rabbit Polyclonal antibody detecting RNASEL in WB. Suitable for Human.

Quick Overview for RNASEL antibody (AA 472-741) (ABIN6146994)

Target: RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNASEL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNASEL Antibody

Binding Specificity: AA 472-741

Sequence: VQELHLSCGY THQDLQPQNI LIDSKKAAHL ADFDKSIKWA GDPQEVKRDL EDLGRLVLYV VKKGSISFED LKAQSNEEVV QLSPDEETKD LIHRLFHPGE HVRDCLSDLL GHPFFWTWES RYRTLRNVGN ESDIKTRKSE SEILRLLQPG PSEHSKSFDK WTTKINECVM KKMNKFYEKR GNFYQNTVGD LLKFIRNLGE HIDEEKHKKM KLKIGDPSLY FQKTFPDLVI YVYTKLQNTE YRKHFPQTHS PNKPQCDGAG GASGLASPGC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 472-741 of human RNASEL (NP_066956.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNASEL

Target: RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))

Alternative Name: RNASEL

Background: This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele.,RNASEL,PRCA1,RNS4,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Immunology & Inflammation,Cytokines,Interferons,Cell Intrinsic Innate Immunity Signaling Pathway,RNASEL

Molecular Weight: 73 kDa/83 kDa

Gene ID: 6041

UniProt: Q05823

Pathways: Hepatitis C