RTN4RL1 antibody (AA 220-420)

Catalog No. ABIN6147298

The Rabbit Polyclonal anti-RTN4RL1 antibody has been validated for WB. It is suitable to detect RTN4RL1 in samples from Human.

Quick Overview for RTN4RL1 antibody (AA 220-420) (ABIN6147298)

Target: RTN4RL1 (Reticulon 4 Receptor-Like 1 (RTN4RL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTN4RL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RTN4RL1 Antibody

Binding Specificity: AA 220-420

Sequence: LRRLTTLFLF NNSLSELQGE CLAPLGALEF LRLNGNPWDC GCRARSLWEW LQRFRGSSSA VPCVSPGLRH GQDLKLLRAE DFRNCTGPAS PHQIKSHTLT TTDRAARKEH HSPHGPTRSK GHPHGPRPGH RKPGKNCTNP RNRNQISKAG AGKQAPELPD YAPDYQHKFS FDIMPTARPK RKGKCARRTP IRAPSGVQQA S

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human RTN4RL1 (NP_848663.1).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:4000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RTN4RL1

Target: RTN4RL1 (Reticulon 4 Receptor-Like 1 (RTN4RL1))

Alternative Name: RTN4RL1

Background: Cell surface receptor. Plays a functionally redundant role in postnatal brain development and in regulating axon regeneration in the adult central nervous system. Contributes to normal axon migration across the brain midline and normal formation of the corpus callosum. Protects motoneurons against apoptosis, protection against apoptosis is probably mediated by MAG. Plays a role in inhibiting neurite outgrowth and axon regeneration via its binding to neuronal chondroitin sulfate proteoglycans. Binds heparin (By similarity. Like other family members, plays a role in restricting the number dendritic spines and the number of synapses that are formed during brain development. Signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton.,RTN4RL1,NGRH2,NgR3,Neuroscience,RTN4RL1

Molecular Weight: 49 kDa

Gene ID: 146760

UniProt: Q86UN2