SARS2 antibody (AA 289-518)

Catalog No. ABIN6147387

This Rabbit Polyclonal antibody specifically detects SARS2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SARS2 antibody (AA 289-518) (ABIN6147387)

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SARS2 Antibody

Binding Specificity: AA 289-518

Sequence: ARFKDLNLAG TAEVGLAGYF MDHTVAFRDL PVRMVCSSTC YRAETNTGQE PRGLYRVHHF TKVEMFGVTG PGLEQSSQLL EEFLSLQMEI LTELGLHFRV LDMPTQELGL PAYRKFDIEA WMPGRGRFGE VTSASNCTDF QSRRLHIMFQ TEAGELQFAH TVNATACAVP RLLIALLESN QQKDGSVLVP PALQSYLGTD RITAPTHVPL QYIGPNQPRK PGLPGQPAVS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-518 of human SARS2 (NP_060297.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SARS2

Target: SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))

Alternative Name: SARS2

Background: This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.,SARS2,SARS,SARSM,SERS,SYS,SerRS,SerRSmt,Epigenetics & Nuclear Signaling,SARS2

Molecular Weight: 58 kDa

Gene ID: 54938

UniProt: Q9NP81