SEC31A antibody (AA 300-500)

Catalog No. ABIN6147491

This Rabbit Polyclonal antibody specifically detects SEC31A in WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for SEC31A antibody (AA 300-500) (ABIN6147491)

Target: SEC31A (SEC31 Homolog A (SEC31A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC31A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SEC31A Antibody

Binding Specificity: AA 300-500

Sequence: PTNTQWCFDI QWCPRNPAVL SAASFDGRIS VYSIMGGSTD GLRQKQVDKL SSSFGNLDPF GTGQPLPPLQ IPQQTAQHSI VLPLKKPPKW IRRPVGASFS FGGKLVTFEN VRMPSHQGAE QQQQQHHVFI SQVVTEKEFL SRSDQLQQAV QSQGFINYCQ KKIDASQTEF EKNVWSFLKV NFEDDSRGKY LELLGYRKED L

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-500 of human SEC31A (NP_055748.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-SEC31A antibody (ABIN6147491)

Fang, Fang, Liu, Hong, Wang, Dong, Ma, Bi, Wang, Xiao: "Identification and subcellular localization of porcine deltacoronavirus accessory protein NS6." in: Virology, Vol. 499, pp. 170-177, (2017) (PubMed).

Target Details for SEC31A

Target: SEC31A (SEC31 Homolog A (SEC31A))

Alternative Name: SEC31A

Background: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.,SEC31A,ABP125,ABP130,HSPC275,HSPC334,SEC31L1,Signal Transduction,SEC31A

Molecular Weight: 56 kDa/105-134 kDa

Gene ID: 22872

UniProt: O94979

Pathways: ER-Nucleus Signaling