P-Selectin antibody (AA 30-200)

Catalog No. ABIN6147503

This Rabbit Polyclonal antibody specifically detects P-Selectin in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for P-Selectin antibody (AA 30-200) (ABIN6147503)

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P-Selectin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-P-Selectin Antibody

Binding Specificity: AA 30-200

Sequence: ISELTNQKEV AAWTYHYSTK AYSWNISRKY CQNRYTDLVA IQNKNEIDYL NKVLPYYSSY YWIGIRKNNK TWTWVGTKKA LTNEAENWAD NEPNNKRNNE DCVEIYIKSP SAPGKWNDEH CLKKKHALCY TASCQDMSCS KQGECLETIG NYTCSCYPGF YGPECEYVRE C

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human CD62P/P-selectin (NP_002996.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P-Selectin

Target: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Alternative Name: CD62P/P-selectin

Background: This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.,SELP,CD62,CD62P,GMP140,GRMP,LECAM3,PADGEM,PSEL,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Blood,CD62P/P-selectin

Molecular Weight: 90 kDa

Gene ID: 6403

UniProt: P16109