SFXN1 antibody (AA 87-322)

Catalog No. ABIN6147693

This Rabbit Polyclonal antibody specifically detects SFXN1 in WB. It exhibits reactivity toward Human.

Quick Overview for SFXN1 antibody (AA 87-322) (ABIN6147693)

Target: SFXN1 (Sideroflexin 1 (SFXN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFXN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SFXN1 Antibody

Binding Specificity: AA 87-322

Sequence: MILIGRMSAQ VPMNMTITGC MMTFYRTTPA VLFWQWINQS FNAVVNYTNR SGDAPLTVNE LGTAYVSATT GAVATALGLN ALTKHVSPLI GRFVPFAAVA AANCINIPLM RQRELKVGIP VTDENGNRLG ESANAAKQAI TQVVVSRILM AAPGMAIPPF IMNTLEKKAF LKRFPWMSAP IQVGLVGFCL VFATPLCCAL FPQKSSMSVT SLEAELQAKI QESHPELRRV YFNKGL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 87-322 of human SFXN1 (NP_073591.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SFXN1

Target: SFXN1 (Sideroflexin 1 (SFXN1))

Alternative Name: SFXN1

Background: Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Transports both D-serine and L-serine. Also able to transport other amino-acids, such as alanine. May be indirectly involved in the transport of a component required for iron utilization into or out of the mitochondria (By similarity.,SFXN1,TCC,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,SFXN1

Molecular Weight: 35 kDa

Gene ID: 94081

UniProt: Q9H9B4

Pathways: Transition Metal Ion Homeostasis