SH3BP2 antibody (AA 392-561)

Catalog No. ABIN6147721

The Rabbit Polyclonal anti-SH3BP2 antibody has been validated for WB. It is suitable to detect SH3BP2 in samples from Human.

Quick Overview for SH3BP2 antibody (AA 392-561) (ABIN6147721)

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SH3BP2 Antibody

Binding Specificity: AA 392-561

Sequence: VPEAMARPAV LPRPEKPQLP HLQRSPPDGQ SFRSFSFEKP RQPSQADTGG DDSDEDYEKV PLPNSVFVNT TESCEVERLF KATSPRGEPQ DGLYCIRNSS TKSGKVLVVW DETSNKVRNY RIFEKDSKFY LEGEVLFVSV GSMVEHYHTH VLPSHQSLLL RHPYGYTGPR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 392-561 of human SH3BP2 (NP_001116153.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SH3BP2

Target: SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))

Alternative Name: SH3BP2

Background: The protein encoded by this gene has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in this gene result in cherubism. Multiple transcript variants encoding different isoforms have been found for this gene.,SH3BP2,3BP-2,3BP2,CRBM,CRPM,RES4-23,Signal Transduction,SH3BP2

Molecular Weight: 10 kDa/62 kDa/65 kDa/68 kDa

Gene ID: 6452

UniProt: P78314

Pathways: TCR Signaling