SIRT4 antibody (AA 29-260)

Catalog No. ABIN6147796

This Rabbit Polyclonal antibody specifically detects SIRT4 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SIRT4 antibody (AA 29-260) (ABIN6147796)

Target: SIRT4 (Sirtuin 4 (SIRT4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SIRT4 Antibody

Binding Specificity: AA 29-260

Sequence: IGLFVPASPP LDPEKVKELQ RFITLSKRLL VMTGAGISTE SGIPDYRSEK VGLYARTDRR PIQHGDFVRS APIRQRYWAR NFVGWPQFSS HQPNPAHWAL STWEKLGKLY WLVTQNVDAL HTKAGSRRLT ELHGCMDRVL CLDCGEQTPR GVLQERFQVL NPTWSAEAHG LAPDGDVFLS EEQVRSFQVP TCVQCGGHLK PDVVFFGDTV NPDKVDFVHK RVKEADSLLV VG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-260 of human SIRT4 (NP_036372.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SIRT4

Target: SIRT4 (Sirtuin 4 (SIRT4))

Alternative Name: SIRT4

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.,SIRT4,SIR2L4,sirtuin 4,Epigenetics & Nuclear Signaling,SIRT4

Molecular Weight: 35 kDa

Gene ID: 23409

UniProt: Q9Y6E7

Pathways: Negative Regulation of Hormone Secretion