SLC25A27 antibody (AA 1-245)

Catalog No. ABIN6147924

This Rabbit Polyclonal antibody specifically detects SLC25A27 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for SLC25A27 antibody (AA 1-245) (ABIN6147924)

Target: SLC25A27 (Solute Carrier Family 25, Member 27 (SLC25A27))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A27 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-SLC25A27 Antibody

Binding Specificity: AA 1-245

Sequence: MSVPEEEERL LPLTQRWPRA SKFLLSGCAA TVAELATFPL DLTKTRLQMQ GEAALARLGD GARESAPYRG MVRTALGIIE EEGFLKLWQG VTPAIYRHVV YSGGRMVTYE HLREVVFGKS EDEHYPLWKS VIGGMMAGVI GQFLANPTDL VKVQMQMEGK RKLEGKPLRF RGVHHAFAKI LAEGGIRGLW AGWVPNIQRA ALVNMGDLTT YDTVKHYLVL NTPLEDNIMT HGLSSDLVGS HKAIQ

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human SLC25A27 (NP_001190981.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SLC25A27

Target: SLC25A27 (Solute Carrier Family 25, Member 27 (SLC25A27))

Alternative Name: SLC25A27

Background: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.,SLC25A27,UCP4,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,SLC25A27

Molecular Weight: 27 kDa/36 kDa

Gene ID: 9481

UniProt: O95847