Sp3 antibody (AA 240-350)

Catalog No. ABIN6148314

This Rabbit Polyclonal antibody specifically detects Sp3 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Sp3 antibody (AA 240-350) (ABIN6148314)

Target: Sp3 (Sp3 Transcription Factor (Sp3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sp3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Sp3 Antibody

Binding Specificity: AA 240-350

Sequence: AIGGSSFPGQ TQVVANVPLG LPGNITFVPI NSVDLDSLGL SGSSQTMTAG INADGHLINT GQAMDSSDNS ERTGERVSPD INETNTDTDL FVPTSSSSQL PVTIDSTGIL Q

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-350 of human SP3 (NP_003102.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Sp3

Target: Sp3 (Sp3 Transcription Factor (Sp3))

Alternative Name: SP3

Background: This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.,SP3,SPR2,Epigenetics & Nuclear Signaling,Transcription Factors,SP3

Molecular Weight: 52 kDa/53 kDa/75 kDa/76 kDa/80 kDa/81 kDa

Gene ID: 6670

UniProt: Q02447