ST14 antibody (AA 566-855)
Quick Overview for ST14 antibody (AA 566-855) (ABIN6148517)
Target
See all ST14 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 566-855
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Sequence
- TCTKHTYRCL NGLCLSKGNP ECDGKEDCSD GSDEKDCDCG LRSFTRQARV VGGTDADEGE WPWQVSLHAL GQGHICGASL ISPNWLVSAA HCYIDDRGFR YSDPTQWTAF LGLHDQSQRS APGVQERRLK RIISHPFFND FTFDYDIALL ELEKPAEYSS MVRPICLPDA SHVFPAGKAI WVTGWGHTQY GGTGALILQK GEIRVINQTT CENLLPQQIT PRMMCVGFLS GGVDSCQGDS GGPLSSVEAD GRIFQAGVVS WGDGCAQRNK PGVYTRLPLF RDWIKENTGV
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 566-855 of human ST14 (NP_068813.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- ST14 (Suppression of Tumorigenicity 14 (ST14))
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Alternative Name
- ST14
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Background
- The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.,ST14,ARCI11,HAI,MT-SP1,MTSP1,PRSS14,SNC19,TADG15,TMPRSS14,ST14
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Molecular Weight
- 94 kDa
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Gene ID
- 6768
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UniProt
- Q9Y5Y6
Target
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