Stabilin 2 (STAB2) (AA 1550-1850) antibody

Catalog No. ABIN6148547

The Rabbit Polyclonal anti- antibody has been validated for WB. It is suitable to detect in samples from Human.

Quick Overview for Stabilin 2 (STAB2) (AA 1550-1850) antibody (ABIN6148547)

Target: Stabilin 2 (STAB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: AA 1550-1850

Sequence: GKVCTLINVC LTKNGGCSEF AICNHTGQVE RTCTCKPNYI GDGFTCRGSI YQELPKNPKT SQYFFQLQEH FVKDLVGPGP FTVFAPLSAA FDEEARVKDW DKYGLMPQVL RYHVVACHQL LLENLKLISN ATSLQGEPIV ISVSQSTVYI NNKAKIISSD IISTNGIVHI IDKLLSPKNL LITPKDNSGR ILQNLTTLAT NNGYIKFSNL IQDSGLLSVI TDPIHTPVTL FWPTDQALHA LPAEQQDFLF NQDNKDKLKE YLKFHVIRDA KVLAVDLPTS TAWKTLQGSE LSVKCGAGRD I

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1550-1850 of human STAB2 (NP_060034.9).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details

Target: Stabilin 2 (STAB2)

Alternative Name: STAB2

Background: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.,STAB2,FEEL2,FELE-2,FELL2,FEX2,HARE,SCARH1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,STAB2

Molecular Weight: 276 kDa

Gene ID: 55576

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process