APOH antibody

Catalog No. ABIN614872

This Goat Polyclonal antibody specifically detects APOH in IHC (p) and EIA. It exhibits reactivity toward Human, Rat, Dog, Pig and Rabbit.

Quick Overview for APOH antibody (ABIN614872)

Target: APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))

Reactivity: Human, Rat, Dog, Pig, Rabbit

Host: Goat

Clonality: Polyclonal

Conjugate: This APOH antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-APOH Antibody

Specificity: This antibody recognizes beta2GP-I. A single precipitin arc is observed with normal plasma. No arc was seen with beta2GP-I deficient plasma.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, porcine, rat, rabbit, canine

Purification: Immunoaffinity chromatography

Immunogen: Human beta2-Glycoprotein-I (beta2GP-I) purified from plasma Genename: APOH

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 2.0 mg/mL

Buffer: 10 mM HEPES, pH 7.4, 0.15 M sodium chloride, 50 % glycerol

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for APOH

Target: APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))

Alternative Name: Apolipoprotein H (Apo H)

Background: Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.Synonyms: APC Inhibitor, Anticardiolipin Cofactor, Apo-H, ApoH, B2G1, B2GPI, Beta-2-glycoprotein I, Beta2GPI

Gene ID: 350

NCBI Accession: NP_000033

UniProt: P02749