SURF1 antibody (AA 80-275)

Catalog No. ABIN6148744

This Rabbit Polyclonal antibody specifically detects SURF1 in WB. It exhibits reactivity toward Human.

Quick Overview for SURF1 antibody (AA 80-275) (ABIN6148744)

Target: SURF1 (Surfeit 1 (SURF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SURF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SURF1 Antibody

Binding Specificity: AA 80-275

Sequence: QVQRRKWKLN LIAELESRVL AEPVPLPADP MELKNLEYRP VKVRGCFDHS KELYMMPRTM VDPVREAREG GLISSSTQSG AYVVTPFHCT DLGVTILVNR GFVPRKKVNP ETRQKGQIEG EVDLIGMVRL TETRQPFVPE NNPERNHWHY RDLEAMARIT GAEPIFIDAN FQSTVPGGPI GGQTRVTLRN EHLQYI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-275 of human SURF1 (NP_003163.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SURF1

Target: SURF1 (Surfeit 1 (SURF1))

Alternative Name: SURF1

Background: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.,SURF1,CMT4K,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,SURF1

Molecular Weight: 31 kDa/33 kDa

Gene ID: 6834

UniProt: Q15526

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process