SYNPO2 antibody (AA 1-300)

Catalog No. ABIN6148777

This anti-SYNPO2 antibody is a Rabbit Polyclonal antibody detecting SYNPO2 in WB. Suitable for Human.

Quick Overview for SYNPO2 antibody (AA 1-300) (ABIN6148777)

Target: SYNPO2 (Synaptopodin 2 (SYNPO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNPO2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SYNPO2 Antibody

Binding Specificity: AA 1-300

Sequence: MGTGDFICIS MTGGAPWGFR LQGGKEQKQP LQVAKIRNQS KASGSGLCEG DEVVSINGNP CADLTYPEVI KLMESITDSL QMLIKRPSSG ISEALISENE NKNLEHLTHG GYVESTTLQI RPATKTQCTE FFLAPVKTEV PLAENQRSGP DCAGSLKEET GPSYQRAPQM PDSQRGRVAE ELILREKVEA VQPGPVVELQ LSLSQERHKG ASGPLVALPG AEKSKSPDPD PNLSHDRIVH INSIPTNEKA DPFLRSSKII QISSGRELRV IQESEAGDAG LPRVEVILDC SDRQKTEGCR

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SYNPO2 (NP_597734.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SYNPO2

Target: SYNPO2 (Synaptopodin 2 (SYNPO2))

Alternative Name: SYNPO2

Background: Has an actin-binding and actin-bundling activity. Can induce the formation of F-actin networks in an isoform-specific manner. At the sarcomeric Z lines is proposed to act as adapter protein that links nascent myofibers to the sarcolemma via ZYX and may play a role in early assembly and stabilization of the Z lines. Involved in autophagosome formation. May play a role in chaperone-assisted selective autophagy (CASA involved in Z lines maintenance in striated muscle under mechanical tension, may link the client-processing CASA chaperone machinery to a membrane-tethering and fusion complex providing autophagosome membranes (By similarity. Involved in regulation of cell migration. May be a tumor suppressor.,SYNPO2,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,SYNPO2

Molecular Weight: 74 kDa/117 kDa/119 kDa/133 kDa/136 kDa

Gene ID: 171024

UniProt: Q9UMS6