TCEB3 antibody (AA 679-798)

Catalog No. ABIN6148938

The Rabbit Polyclonal anti-TCEB3 antibody has been validated for WB and IF. It is suitable to detect TCEB3 in samples from Human.

Quick Overview for TCEB3 antibody (AA 679-798) (ABIN6148938)

Target: TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TCEB3 Antibody

Binding Specificity: AA 679-798

Sequence: ANKPKGRQAK MAFVNSVAKP PRDVRRRQEK FGTGGAAVPE KIKIKPAPYP MGSSHASASS ISFNPSPEEP AYDGPSTSSA HLAPVVSSTV SYDPRKPTVK KIAPMMAKTI KAFKNRFSRR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 679-798 of human TCEB3 (NP_003189.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TCEB3

Target: TCEB3 (Transcription Elongation Factor B (SIII), Polypeptide 3 (110kDa, Elongin A) (TCEB3))

Alternative Name: TCEB3

Background: This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation.,ELOA,SIII,SIII p110,TCEB3,TCEB3A,SIIIp110,elongin-A,Epigenetics & Nuclear Signaling,TCEB3

Molecular Weight: 89 kDa

Gene ID: 6924

UniProt: Q14241