TDRD3 antibody (AA 1-220)

Catalog No. ABIN6148978

The Rabbit Polyclonal anti-TDRD3 antibody has been validated for WB. It is suitable to detect TDRD3 in samples from Human.

Quick Overview for TDRD3 antibody (AA 1-220) (ABIN6148978)

Target: TDRD3 (Tudor Domain Containing 3 (TDRD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDRD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TDRD3 Antibody

Binding Specificity: AA 1-220

Sequence: MLRLQMTDGH ISCTAVEFSY MSKISLNTPP GTKVKLSGIV DIKNGFLLLN DSNTTVLGGE VEHLIEKWEL QRSLSKHNRS NIGTEGGPPP FVPFGQKCVS HVQVDSRELD RRKTLQVTMP VKPTNDNDEF EKQRTAAIAE VAKSKETKTF GGGGGGARSN LNMNAAGNRN REVLQKEKST KSEGKHEGVY RELVDEKALK HITEMGFSKE ASRQALMDNG

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human TDRD3 (NP_110421.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TDRD3

Target: TDRD3 (Tudor Domain Containing 3 (TDRD3))

Alternative Name: TDRD3

Background: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR in dimethylarginine-containing proteins.,TDRD3,Epigenetics & Nuclear Signaling,RNA Binding,Neuroscience,Neurodegenerative Diseases,TDRD3

Molecular Weight: 73 kDa/83 kDa

Gene ID: 81550

UniProt: Q9H7E2