Tescalcin antibody (AA 135-214)

Catalog No. ABIN6149009

The Rabbit Polyclonal anti-Tescalcin antibody has been validated for WB. It is suitable to detect Tescalcin in samples from Human.

Quick Overview for Tescalcin antibody (AA 135-214) (ABIN6149009)

Target: Tescalcin (TESC)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tescalcin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tescalcin Antibody

Binding Specificity: AA 135-214

Sequence: YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME PDQVYEGITF EDFLKIWQGI DIETKMHVRF LNMETMALCH

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 135-214 of human TESC (NP_060369.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Tescalcin

Target: Tescalcin (TESC)

Alternative Name: TESC

Background: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+/H(+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.,TESC,CHP3,TSC,tescalcin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neuroscience,Calcium Signaling,TESC

Molecular Weight: 18 kDa/21 kDa/24 kDa

Gene ID: 54997

UniProt: Q96BS2

Pathways: Proton Transport