TNFAIP6 antibody (AA 18-277)
Quick Overview for TNFAIP6 antibody (AA 18-277) (ABIN6149294)
Target
See all TNFAIP6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 18-277
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Sequence
- WGFKDGIFHN SIWLERAAGV YHREARSGKY KLTYAEAKAV CEFEGGHLAT YKQLEAARKI GFHVCAAGWM AKGRVGYPIV KPGPNCGFGK TGIIDYGIRL NRSERWDAYC YNPHAKECGG VFTDPKQIFK SPGFPNEYED NQICYWHIRL KYGQRIHLSF LDFDLEDDPG CLADYVEIYD SYDDVHGFVG RYCGDELPDD IISTGNVMTL KFLSDASVTA GGFQIKYVAM DPVSKSSQGK NTSTTSTGNK NFLAGRFSHL
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 18-277 of human TNFAIP6 (NP_009046.2).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- TNFAIP6 (Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6))
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Alternative Name
- TNFAIP6
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Background
- The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.,TNFAIP6,TSG-6,TSG6,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,TNFAIP6
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Molecular Weight
- 31 kDa
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Gene ID
- 7130
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UniProt
- P98066
Target
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