TNNI3 antibody (AA 1-210)

Catalog No. ABIN6149358

This Rabbit Polyclonal antibody specifically detects TNNI3 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for TNNI3 antibody (AA 1-210) (ABIN6149358)

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNNI3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-TNNI3 Antibody

Binding Specificity: AA 1-210

Sequence: MADGSSDAAR EPRPAPAPIR RRSSNYRAYA TEPHAKKKSK ISASRKLQLK TLLLQIAKQE LEREAEERRG EKGRALSTRC QPLELAGLGF AELQDLCRQL HARVDKVDEE RYDIEAKVTK NITEIADLTQ KIFDLRGKFK RPTLRRVRIS ADAMMQALLG ARAKESLDLR AHLKQVKKED TEKENREVGD WRKNIDALSG MEGRKKKFES

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human TNNI3 (NP_000354.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Alternative Name: TNNI3

Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).,TNNI3,CMD1FF,CMD2A,CMH7,RCM1,TNNC1,cTnI,troponin I3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Stem Cells,Cardiovascular,Cardiovascular Markers,Cardiomyocytes,Angiogenesis,Heart,Contractility,TNNI3

Molecular Weight: 24 kDa

Gene ID: 7137

UniProt: P19429