TRIP12 antibody (AA 1-240)

Catalog No. ABIN6149543

This Rabbit Polyclonal antibody specifically detects TRIP12 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for TRIP12 antibody (AA 1-240) (ABIN6149543)

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-TRIP12 Antibody

Binding Specificity: AA 1-240

Sequence: MSNRPNNNPG GSLRRSQRNT AGAQPQDDSI GGRSHLGQAK HKGYSPPESR KSNSKAPKVQ SNTTSELSRG HLSKRSCSSS SAVIVPQPED PDRANTSERQ KTGQVPKKDN SRGVKRSASP DYNRTNSPSS AKKPKALQHT ESPSETNKPH SKSKKRHLDQ EQQLKSAQSP STSKAHTRKS GATGGSRSQK RKRTESSCVK SGSGSESTGA EERSAKPTKL ASKSATSAKA GCSTITDSSS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human TRIP12 (NP_001271143.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRIP12

Target: TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))

Alternative Name: TRIP12

Background: The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.,TRIP12,TRIP-12,ULF,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,TRIP12

Molecular Weight: 192 kDa/220 kDa/223 kDa/225 kDa

Gene ID: 9320

UniProt: Q14669

Pathways: Nuclear Hormone Receptor Binding