C16orf57 antibody (AA 1-265)

Catalog No. ABIN6149979

The Rabbit Polyclonal anti-C16orf57 antibody has been validated for WB. It is suitable to detect C16orf57 in samples from Human.

Quick Overview for C16orf57 antibody (AA 1-265) (ABIN6149979)

Target: C16orf57 (USB1) (U6 SnRNA Biogenesis 1 (USB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C16orf57 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C16orf57 Antibody

Binding Specificity: AA 1-265

Sequence: MSAAPLVGYS SSGSEDESED GMRTRPGDGS HRRGQSPLPR QRFPVPDSVL NMFPGTEEGP EDDSTKHGGR VRTFPHERGN WATHVYVPYE AKEEFLDLLD VLLPHAQTYV PRLVRMKVFH LSLSQSVVLR HHWILPFVQA LKARMTSFHR FFFTANQVKI YTNQEKTRTF IGLEVTSGHA QFLDLVSEVD RVMEEFNLTT FYQDPSFHLS LAWCVGDARL QLEGQCLQEL QAIVDGFEDA EVLLRVHTEQ VRCKSGNKFF SMPLK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human USB1 (NP_078874.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C16orf57

Target: C16orf57 (USB1) (U6 SnRNA Biogenesis 1 (USB1))

Alternative Name: USB1

Background: This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.,USB1,C16orf57,HVSL1,Mpn1,PN,hUsb1,Cell Biology & Developmental Biology,USB1

Molecular Weight: 20 kDa/28 kDa/30 kDa

Gene ID: 79650

UniProt: Q9BQ65