YARS antibody (AA 1-300)

Catalog No. ABIN6150324

This Rabbit Polyclonal antibody specifically detects YARS in WB and IP. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for YARS antibody (AA 1-300) (ABIN6150324)

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-YARS Antibody

Binding Specificity: AA 1-300

Sequence: MGDAPSPEEK LHLITRNLQE VLGEEKLKEI LKERELKIYW GTATTGKPHV AYFVPMSKIA DFLKAGCEVT ILFADLHAYL DNMKAPWELL ELRVSYYENV IKAMLESIGV PLEKLKFIKG TDYQLSKEYT LDVYRLSSVV TQHDSKKAGA EVVKQVEHPL LSGLLYPGLQ ALDEEYLKVD AQFGGIDQRK IFTFAEKYLP ALGYSKRVHL MNPMVPGLTG SKMSSSEEES KIDLLDRKED VKKKLKKAFC EPGNVENNGV LSFIKHVLFP LKSEFVILRD EKWGGNKTYT AYVDLEKDFA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human YARS (NP_003671.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IP,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-YARS antibody (ABIN6150324)

Zhang, Zhai, Tang, Cheng, Li, Wang, Zhu: "Quantitative proteome-based systematic identification of SIRT7 substrates." in: Proteomics, Vol. 17, Issue 13-14, (2017) (PubMed).

Target Details for YARS

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Alternative Name: YARS

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.,YARS,CMTDIC,TYRRS,YRS,YTS,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Immunology & Inflammation,Cytokines,YARS

Molecular Weight: 59 kDa

Gene ID: 8565

UniProt: P54577