CD48 antibody (CF®647)
Quick Overview for CD48 antibody (CF®647) (ABIN6187454)
Target
See all CD48 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Mouse Monoclonal anti-CD48 (156-4H9), CF647 Conjugate
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Characteristics
- Reacts with human CD48, a 45 kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Human CD48 protein
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Isotype
- IgG2a kappa
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Application Notes
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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Comment
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Daudi, JY, Raji, Jurkat, and human lymphocytes. Human lymph node and tonsil.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100 μg/mL
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Buffer
- PBS/0.1 % BSA/0.05 % azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Protect from light
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- CD48
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Alternative Name
- CD48
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Background
- B-cell activation marker|B-lymphocyte activation marker BLAST-1|BCM1 surface antigen|BLAST1|CD48 antigen (B cell membrane protein)|Signaling lymphocytic activation molecule 2 (SLAMF2)|SLAM family member 2
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Molecular Weight
- 45 kDa
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Gene ID
- 962, 243564
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UniProt
- P09326
Target
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