LTA antibody (AA 40-205)

Catalog No. ABIN3022128

This Rabbit Polyclonal antibody specifically detects LTA in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for LTA antibody (AA 40-205) (ABIN3022128)

Target: LTA (Lymphotoxin-alpha (LTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LTA Antibody

Binding Specificity: AA 40-205

Sequence: LTPSAAQTAR QHPKMHLAHS TLKPAAHLIG DPSKQNSLLW RANTDRAFLQ DGFSLSNNSL LVPTSGIYFV YSQVVFSGKA YSPKATSSPL YLAHEVQLFS SQYPFHVPLL SSQKMVYPGL QEPWLHSMYH GAAFQLTQGD QLSTHTDGIP HLVLSPSTVF FGAFAL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-205 of human LTA (NP_000586.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LTA

Target: LTA (Lymphotoxin-alpha (LTA))

Alternative Name: LTA

Target Type: Chemical

Background: The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.,LTA,LT,TNFB,TNFSF1,TNLG1E,LT-alpha,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TNF,Immunology & Inflammation,Cytokines,TNF,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Angiogenesis,Angiogenic growth factors,LTA

Molecular Weight: 22 kDa

Gene ID: 4049

UniProt: P01374

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process