TFAP2C antibody (AA 114-147)
Quick Overview for TFAP2C antibody (AA 114-147) (ABIN6242775)
Target
See all TFAP2C AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 114-147
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TFAP2C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 114-147 amino acids from the central region of human TFAP2C.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- TFAP2C (Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C))
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Alternative Name
- TFAP2C
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Background
- Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
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Molecular Weight
- 49177
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UniProt
- Q92754
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Pathways
- Stem Cell Maintenance
Target
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