RPS8 antibody (N-Term)

Catalog No. ABIN6242934

There are 2+ publications for this product available. The Rabbit Polyclonal anti-RPS8 antibody has been validated for WB and FACS. It is suitable to detect RPS8 in samples from Human and Mouse.

Quick Overview for RPS8 antibody (N-Term) (ABIN6242934)

Target: RPS8 (Ribosomal Protein S8 (RPS8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS8 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB23630

Product Details anti-RPS8 Antibody

Binding Specificity: AA 1-28, N-Term

Predicted Reactivity: B, Pr, Rat, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RPS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-28 amino acids from the N-terminal region of human RPS8.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-RPS8 antibody (ABIN6242934)

Sbarrato, Horvilleur, Pöyry, Hill, Chaplin, Spriggs, Stoneley, Wilson, Jayne, Vulliamy, Beck, Dokal, Dyer, Yeomans, Packham, Bushell, Wagner, Willis: "A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment." in: Cell death & disease, Vol. 7, Issue 6, pp. e2249, (2017) (PubMed).

Knight, Willis, Milner: "Active regulator of SIRT1 is required for ribosome biogenesis and function." in: Nucleic acids research, Vol. 41, Issue 7, pp. 4185-97, (2013) (PubMed).

Target Details for RPS8

Target: RPS8 (Ribosomal Protein S8 (RPS8))

Alternative Name: RPS8

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS8 is a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm.

Molecular Weight: 24205

NCBI Accession: NP_001003

UniProt: P62241