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BCL2L1 antibody (C-Term)

This Rabbit Polyclonal antibody specifically detects BCL2L1 in WB. It exhibits reactivity toward Human and Ratand has been mentioned in 1 publication.
Catalog No. ABIN6243062

Quick Overview for BCL2L1 antibody (C-Term) (ABIN6243062)

Target

See all BCL2L1 Antibodies
BCL2L1 (BCL2-Like 1 (BCL2L1))

Reactivity

  • 235
  • 135
  • 118
  • 51
  • 25
  • 12
  • 10
  • 10
  • 5
  • 5
  • 4
  • 2
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  • 1
Human, Rat

Host

  • 169
  • 95
  • 1
Rabbit

Clonality

  • 151
  • 114
Polyclonal

Conjugate

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  • 27
  • 11
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
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  • 4
  • 4
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This BCL2L1 antibody is un-conjugated

Application

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  • 99
  • 65
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  • 56
  • 43
  • 32
  • 28
  • 28
  • 27
  • 21
  • 14
  • 10
  • 7
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  • 4
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB)

Clone

RB50807
  • Binding Specificity

    • 30
    • 25
    • 19
    • 16
    • 16
    • 15
    • 12
    • 10
    • 8
    • 5
    • 4
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 195-229, C-Term

    Predicted Reactivity

    M, Pig

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This BCL2L1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 195-229 amino acids from the C-terminal region of human BCL2L1.

    Isotype

    Ig Fraction
  • Application Notes

    WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Expiry Date

    6 months
  • Hu, Kuo, Senadi, Chang, Wang: "Photodynamic Therapy Using Indolines-Fused-Triazoles Induces Mitochondrial Apoptosis in Human Non-Melanoma BCC Cells." in: Anticancer research, Vol. 37, Issue 10, pp. 5499-5505, (2017) (PubMed).

  • Target

    BCL2L1 (BCL2-Like 1 (BCL2L1))

    Alternative Name

    BCL2L1

    Background

    Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage- dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(S) promotes apoptosis.

    Molecular Weight

    26049

    UniProt

    Q07817

    Pathways

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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