KLF4 antibody (AA 321-354)

Catalog No. ABIN6243711

The Rabbit Polyclonal anti-KLF4 antibody has been validated for WB and FACS. It is suitable to detect KLF4 in samples from Mouse.

Quick Overview for KLF4 antibody (AA 321-354) (ABIN6243711)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB50946

Product Details anti-KLF4 Antibody

Binding Specificity: AA 321-354

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Klf4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 321-354 amino acids from the Central region of mouse Klf4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Alternative Name: Klf4

Background: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription (By similarity).

Molecular Weight: 51880

UniProt: Q60793

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance