This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This NACC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 324-358 amino acids from the Central region of human NACC1.
NACC1
Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Pig, Bat, Hamster, Xenopus laevis
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:1000. WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Target
NAC1 (NACC1)
(Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
Alternative Name
NACC1
Background
Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.