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PHC1 antibody (AA 308-342)

The Rabbit Polyclonal anti-PHC1 antibody has been validated for WB. It is suitable to detect PHC1 in samples from Human.
Catalog No. ABIN6244140

Quick Overview for PHC1 antibody (AA 308-342) (ABIN6244140)

Target

See all PHC1 Antibodies
PHC1 (Polyhomeotic-Like 1 (PHC1))

Reactivity

  • 42
  • 11
  • 10
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Host

  • 36
  • 6
Rabbit

Clonality

  • 38
  • 4
Polyclonal

Conjugate

  • 17
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PHC1 antibody is un-conjugated

Application

  • 13
  • 13
  • 13
  • 11
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB)

Clone

RB54227
  • Binding Specificity

    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 308-342

    Predicted Reactivity

    M

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This PHC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 308-342 amino acids from human PHC1.

    Isotype

    Ig Fraction
  • Application Notes

    WB: 1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Expiry Date

    6 months
  • Target

    PHC1 (Polyhomeotic-Like 1 (PHC1))

    Alternative Name

    PHC1

    Background

    Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression.

    Molecular Weight

    105534

    UniProt

    P78364
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