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TSG101 antibody

This anti-TSG101 antibody is a Mouse Monoclonal antibody detecting TSG101 in WB. Suitable for Human.
Catalog No. ABIN6244288

Quick Overview for TSG101 antibody (ABIN6244288)

Target

See all TSG101 Antibodies
TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reactivity

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Human

Host

  • 68
  • 14
Mouse

Clonality

  • 57
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Monoclonal

Conjugate

  • 57
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This TSG101 antibody is un-conjugated

Application

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Western Blotting (WB)

Clone

1883CT788-47-15-46
  • Purification

    This antibody is purified through a protein G column, followed by dialysis against PBS.

    Immunogen

    This antibody is generated from a mouse immunized with a recombinant protein from human.

    Isotype

    IgG1 kappa
  • Application Notes

    WB: 1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Expiry Date

    6 months
  • Target

    TSG101 (Tumor Susceptibility Gene 101 (TSG101))

    Alternative Name

    TSG101

    Background

    Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.

    Molecular Weight

    43944

    UniProt

    Q99816
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