TSG101 antibody
Quick Overview for TSG101 antibody (ABIN6244288)
Target
See all TSG101 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purification
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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Immunogen
- This antibody is generated from a mouse immunized with a recombinant protein from human.
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Isotype
- IgG1 kappa
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Application Notes
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- TSG101 (Tumor Susceptibility Gene 101 (TSG101))
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Alternative Name
- TSG101
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Background
- Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis, the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
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Molecular Weight
- 43944
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UniProt
- Q99816
Target
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