Progesterone antibody

Catalog No. ABIN6252523

The Mouse Monoclonal anti-Progesterone antibody has been validated for ELISA, RIA and WB. It is suitable to detect Progesterone in samples from .

Quick Overview for Progesterone antibody (ABIN6252523)

Target: Progesterone

Reactivity: Please inquire

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone antibody is un-conjugated

Application: ELISA, Radioimmunoassay (RIA), Western Blotting (WB)

Clone: 6-5E-10B

Product Details anti-Progesterone Antibody

Purification: Protein G affinity chromatography

Immunogen: Progesterone- 11a-hemisuccinate conjugated to bovine serum albumin (Pr11a-HMS-BSA) was used as the immunogen for the Progesterone antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: ELISA (For coating order Ab without BSA)

Immunohistochemistry (not evaluated)

Radioimmnoassay (RIA)

Optimal dilution of the Progesterone antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Target Details for Progesterone

Target: Progesterone

Target Type: Hormone

Background: This mAb is specific for progesterone. It exhibits minimal cross reactivity with related compounds in ELISA. It reacts with Progesterone-11a-HMS-BSA: 100 % , 5-beta-Pregnane-3,20-dione: 48 %, 5-alpha-Pregnane-3,20-dione: 26.4 %, 17-alpha-Hydroxyprogesterone: 2.5 % and 20-alpha-Hydroxyprogesterone: 0.04 %. Progesterone is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Thus, progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Luteinized theca cells of normal ovary secrete progesterone. The determination of progesterone concentrations in the body fluids is of great value for endocrinological investigations in women. This mAb may prove useful in identification of ovarian tumors.