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Histone 3 antibody (H3K18ac)

This anti-Histone 3 antibody is a Rabbit Polyclonal antibody detecting Histone 3 in WB, IHC, IF, ELISA and ICC. Suitable for Human, Mouse and Rat.
Catalog No. ABIN6254860

Quick Overview for Histone 3 antibody (H3K18ac) (ABIN6254860)

Target

See all Histone 3 (H3) Antibodies
Histone 3 (H3) (Histone H3 (H3))

Reactivity

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Human, Mouse, Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Histone 3 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
  • Binding Specificity

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    H3K18ac

    Specificity

    Acetyl-Histone H3 (Lys18) Antibody detects endogenous levels of total Histone H3 protein only when acetylated at lysine18.

    Cross-Reactivity

    Human, Mouse (Murine), Rat (Rattus)

    Purification

    affinity purification

    Immunogen

    The antiserum was produced against synthesized peptide derived from human Histone H3 around the acetylated site of Lys18.

    Isotype

    IgG
  • Application Notes

    WB: 1:500~1:2000 IHC: 1:50~1:200 IF 1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS,  pH 7.4,50 % glycerol.
  • Target

    Histone 3 (H3) (Histone H3 (H3))

    Alternative Name

    Histone H3

    Background

    Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

    Gene: HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J

    Molecular Weight

    15 kDa

    Gene ID

    8, 350, 835

    UniProt

    P68431, Q71DI3, P84243
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