GATA1 antibody (pSer142)
Quick Overview for GATA1 antibody (pSer142) (ABIN6254982)
Target
See all GATA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer142
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Specificity
- Phospho-GATA1 (Ser142) Antibody detects endogenous levels of GATA1 only when phosphorylated at Serine 142.
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Predicted Reactivity
- Pig,Sheep,Rabbit
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Purification
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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Immunogen
- A synthesized peptide derived from human GATA1 around the phosphorylation site of Ser142.
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IP, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
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Expiry Date
- 12 months
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- GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
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Alternative Name
- GATA1
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Background
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Description: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:24245781).
Gene: GATA1
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Molecular Weight
- 43kDa
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Gene ID
- 2623
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UniProt
- P15976
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Target
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