PLCE1 antibody

Catalog No. ABIN6257434

This anti-PLCE1 antibody is a Rabbit Polyclonal antibody detecting PLCE1 in WB, IHC and ELISA. Suitable for Mouse and Human.

Quick Overview for PLCE1 antibody (ABIN6257434)

Target: PLCE1 (Phospholipase C, epsilon 1 (PLCE1))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLCE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PLCE1 Antibody

Specificity: PLCE1 antibody detects endogenous levels of total PLCE1

Cross-Reactivity: Human, Mouse (Murine)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for PLCE1

Target: PLCE1 (Phospholipase C, epsilon 1 (PLCE1))

Alternative Name: PLCE1

Background:

Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.

Gene: PLCE1

Gene ID: 51196

UniProt: Q9P212

Pathways: EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling