CYP2W1 antibody (Internal Region)

Catalog No. ABIN6258069

The Rabbit Polyclonal anti-CYP2W1 antibody has been validated for WB, IHC, ELISA, IF and ICC. It is suitable to detect CYP2W1 in samples from Human, Mouse and Rat.

Quick Overview for CYP2W1 antibody (Internal Region) (ABIN6258069)

Target: CYP2W1 (Cytochrome P450, Family 2, Subfamily W, Polypeptide 1 (CYP2W1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2W1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-CYP2W1 Antibody

Binding Specificity: Internal Region

Specificity: Cytochrome P450 2W1 Antibody detects endogenous levels of total Cytochrome P450 2W1.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 2W1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CYP2W1

Target: CYP2W1 (Cytochrome P450, Family 2, Subfamily W, Polypeptide 1 (CYP2W1))

Alternative Name: CYP2W1

Background:

Description: Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Active also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743).

Gene: CYP2W1

Molecular Weight: 55 kDa

Gene ID: 54905

UniProt: Q8TAV3