GPR109 antibody

Catalog No. ABIN6258971

This Rabbit Polyclonal antibody specifically detects GPR109 in ELISA, WB, IF and ICC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GPR109 antibody (ABIN6258971)

Target: GPR109 (G Protein-Coupled Receptor 109 (GPR109))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR109 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-GPR109 Antibody

Specificity: GPR109 Antibody detects endogenous levels of total GPR109

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide

Isotype: IgG

Application Details

Application Notes: WB 1:500~1:1000 IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for GPR109

Target: GPR109 (G Protein-Coupled Receptor 109 (GPR109))

Alternative Name: GPR109

Background:

Description: Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.

Gene: HCAR3

Molecular Weight: 45 kDa

Gene ID: 8843

UniProt: P49019, Q8TDS4