CREB3L3 antibody (Internal Region)

Catalog No. ABIN6259626

The Rabbit Polyclonal anti-CREB3L3 antibody has been validated for WB and ELISA. It is suitable to detect CREB3L3 in samples from Human, Mouse and Rat.

Quick Overview for CREB3L3 antibody (Internal Region) (ABIN6259626)

Target: CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB3L3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CREB3L3 Antibody

Binding Specificity: Internal Region

Specificity: CREB3L3 Antibody detects endogenous levels of total CREB3L3.

Predicted Reactivity: Pig,Bovine,Sheep,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human CREB3L3, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Expiry Date: 12 months

Target Details for CREB3L3

Target: CREB3L3 (cAMP Responsive Element Binding Protein 3-Like 3 (CREB3L3))

Alternative Name: CREB3L3

Background:

Description: Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). Seems to function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression.

Gene: CREB3L3

Molecular Weight: 49 kDa

Gene ID: 84699

UniProt: Q68CJ9

Pathways: Thyroid Hormone Synthesis