CYP4F8 antibody (C-Term)

Catalog No. ABIN6261206

This Rabbit Polyclonal antibody specifically detects CYP4F8 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CYP4F8 antibody (C-Term) (ABIN6261206)

Target: CYP4F8 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 8 (CYP4F8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP4F8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CYP4F8 Antibody

Binding Specificity: C-Term

Specificity: Cytochrome P450 4F8 Antibody detects endogenous levels of total Cytochrome P450 4F8.

Predicted Reactivity: Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 4F8, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for CYP4F8

Target: CYP4F8 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 8 (CYP4F8))

Alternative Name: CYP4F8

Background:

Description: Hydroxylates arachidonic acid (20:4n-6) to (18R)-hydroxyarachidonate. Shows little activity against prostaglandin (PG) D2, PGE1, PGE2, PGF2alpha, and leukotriene B4. Catalyzes omega-2 and omega-3-hydroxylation of PGH1 and PGH2. Catalyzes epoxidation of 4,7,10,13,16,19-(Z)-docosahexaenoic acid (22:6n-3) and 7,10,13,16,19-(Z)-docosapentaenoic acid (22:5n-3) and omega-3-hydroxylation of 4,7,10,13,16-(Z)-docosapentaenoic acid (22:5n-6). Catalyzes hydroxylation of PGI2 and carbaprostacyclin.

Gene: CYP4F8

Molecular Weight: 60 kDa

Gene ID: 11283

UniProt: P98187