Gelsolin antibody (C-Term)

Catalog No. ABIN6261937

This anti-Gelsolin antibody is a Rabbit Polyclonal antibody detecting Gelsolin in WB and ELISA. Suitable for Human.

Quick Overview for Gelsolin antibody (C-Term) (ABIN6261937)

Target: Gelsolin (GSN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gelsolin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Gelsolin Antibody

Binding Specificity: C-Term

Specificity: Gelsolin Antibody detects endogenous levels of total Gelsolin.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Gelsolin, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Gelsolin

Target: Gelsolin (GSN)

Alternative Name: GSN

Background:

Description: Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.

Gene: GSN

Molecular Weight: 86 kDa

Gene ID: 2934

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy