ID1 antibody (Internal Region)

Catalog No. ABIN6262441

This anti-ID1 antibody is a Rabbit Polyclonal antibody detecting ID1 in WB, ELISA, IF, IHC and ICC. Suitable for Human, Mouse and Rat.

Quick Overview for ID1 antibody (Internal Region) (ABIN6262441)

Target: ID1 (Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ID1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-ID1 Antibody

Binding Specificity: Internal Region

Specificity: Id1 Antibody detects endogenous levels of total Id1.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Id1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000, IHC 1:200, IF/ICC, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ID1

Target: ID1 (Inhibitor of DNA Binding 1, Dominant Negative Helix-Loop-Helix Protein (ID1))

Alternative Name: ID1

Background:

Description: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity).

Gene: ID1

Molecular Weight: 22kDa

Gene ID: 3397

UniProt: P41134