PPP1R12A antibody (Myosin Phosphatase, Target Subunit 1)

Details for Product anti-PPP1R12A Antibody No. ABIN6263491
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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137
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10
9
9
5
5
3
3
3
3
2
1
Host
Rabbit
172
1
1
Clonality
Polyclonal
Conjugate
This PPP1R12A antibody is un-conjugated
9
9
9
9
9
9
9
2
2
2
2
2
2
2
1
Application
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
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52
51
28
21
9
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2
1
1
Options
Immunogen A synthesized peptide derived from human MYPT1
Isotype IgG
Specificity MYPT1 Antibody detects endogenous levels of total MYPT1
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Antigen
Alternative Name MYPT1 (PPP1R12A Antibody Abstract)
Background

Description: Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

Gene: PPP1R12A

Molecular Weight 115 kDa
Gene ID 4659
UniProt O14974
Pathways M Phase
Application Notes WB 1:500-1:2000,IHC 1:50-1:200
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) antibody (ABIN6263491) Western blot analysis of MYPT1 expression in mouse brain tissue extract.
Image no. 2 for anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) antibody (ABIN6263491) ABIN6268990 at 1/100 staining Mouse lung tissue by IHC-P. The sample was formaldehyde...
Image no. 3 for anti-Myosin Phosphatase, Target Subunit 1 (PPP1R12A) antibody (ABIN6263491) Western blot analysis of MYPT1 expression in NIH/3T3 cell extract.The lane on the lef...
Product cited in: Xiaojun, Yan, Hong, Xianghong, Shifeng, Dingjie, Xuemin, Lijuan, Bonan, Zhongqiu, Ruimin, Brann, Fang: "Acetylated α-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica." in: Scientific reports, Vol. 6, pp. 32257, 2018 (PubMed).