PPP1R12A antibody (Ser507)

Catalog No. ABIN6242457

The Rabbit Polyclonal anti-PPP1R12A antibody is suitable to detect PPP1R12A in samples from Human and Mouse. It has been validated for WB.

Quick Overview for PPP1R12A antibody (Ser507) (ABIN6242457)

Target: PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R12A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB56872

Product Details anti-PPP1R12A Antibody

Binding Specificity: AA 481-514, Ser507

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MYPT1 (Ser507) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 481-514 amino acids from the human MYPT1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:4000. WB: 1:4000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PPP1R12A

Target: PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Alternative Name: MYPT1

Background: Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity.

Molecular Weight: 115281

UniProt: O14974

Pathways: M Phase