Peroxiredoxin 6 antibody (Internal Region)

Catalog No. ABIN6264413

This Rabbit Polyclonal antibody specifically detects Peroxiredoxin 6 in WB, IHC, ELISA, ICC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Peroxiredoxin 6 antibody (Internal Region) (ABIN6264413)

Target: Peroxiredoxin 6 (PRDX6)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-Peroxiredoxin 6 Antibody

Binding Specificity: Internal Region

Specificity: Peroxiredoxin 6 Antibody detects endogenous levels of total Peroxiredoxin 6.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Peroxiredoxin 6, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for Peroxiredoxin 6

Target: Peroxiredoxin 6 (PRDX6)

Alternative Name: PRDX6

Background:

Description: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Can reduce H2O2 and short chain organic, fatty acid, and phospholipid hydroperoxides. Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl grup of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity). These activities are dependent on binding to phospholipids at acidic  pH and to oxidized phospholipds at cytosolic  pH . Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis.

Gene: PRDX6

Molecular Weight: 25kDa

Gene ID: 9588

UniProt: P30041