PTGES3 antibody (C-Term)
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- Target See all PTGES3 Antibodies
- PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTGES3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- P23 Antibody detects endogenous levels of total p23.
- Predicted Reactivity
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human p23, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product PTGES3 Primary Antibody
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anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) (AA 1-160) antibody
PTGES3 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3H1-2A8 unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) (AA 1-161) antibodyPTGES3 Reactivity: Human WB, ELISA, IHC, IHC (p) Host: Mouse Monoclonal 3H1-2A8 unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) antibodyKO Validated PTGES3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) (AA 79-128) antibodyPTGES3 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) antibodyPTGES3 Reactivity: Human, Mouse, Guinea Pig, Rabbit, Chicken, Saccharomyces cerevisiae, Pig WB, ELISA, IHC, IHC (p), IP Host: Mouse Monoclonal JJ6 unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) (AA 1-130) antibodyPTGES3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) (pSer113) antibodyPTGES3 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) (AA 31-130) antibodyPTGES3 Reactivity: Human, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) (AA 1-160) antibodyPTGES3 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Prostaglandin E Synthase 3 (Cytosolic) (PTGES3) (C-Term) antibodyPTGES3 Reactivity: Human, Rat, Mouse, Guinea Pig, Rabbit, Cow, Dog, Horse, Pig, Zebrafish (Danio rerio), Monkey, Bat WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))
- Alternative Name
- PTGES3 (PTGES3 Products)
- Background
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Description: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).
Gene: PTGES3
- Molecular Weight
- 19kDa
- Gene ID
- 10728
- UniProt
- Q15185
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Cellular Glucan Metabolic Process
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