TRPC4AP antibody (N-Term)
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- Target See all TRPC4AP Antibodies
- TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TRPC4AP antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- TRPC4AP Antibody detects endogenous levels of total TRPC4AP.
- Predicted Reactivity
- Bovine,Horse,Sheep,Dog
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TRPC4AP, corresponding to a region within N-terminal amino acids.
- Isotype
- IgG
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anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP) (AA 341-451) antibody
TRPC4AP Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP) antibodyTRPC4AP Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP) (AA 49-75), (N-Term) antibodyTRPC4AP Reactivity: Human WB Host: Rabbit Polyclonal RB38628 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP) (Internal Region) antibodyVerified TRPC4AP Reactivity: Human WB, ELISA Host: Goat Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP) (AA 1-797) antibodyTRPC4AP Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP) (AA 341-451) antibodyTRPC4AP Reactivity: Human ELISA Host: Mouse Monoclonal 3G4 unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- TRPC4AP (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 Associated Protein (TRPC4AP))
- Alternative Name
- TRPC4AP (TRPC4AP Products)
- Background
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Description: Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca2+ storage reduction in response to CHRM1.
Gene: TRPC4AP
- Molecular Weight
- 91 kDa
- Gene ID
- 26133
- UniProt
- Q8TEL6
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