A1CF antibody
Quick Overview for A1CF antibody (ABIN6291254)
Target
See all A1CF AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Purification
- Affinity purification
-
Immunogen
- Recombinant Protein of human A1CF
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB 1:500 - 1:2000
-
Comment
-
Widely expressed with highest levels in brain, liver, pancreas, colon and spleen
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
-
-
- A1CF (APOBEC1 Complementation Factor (A1CF))
-
Alternative Name
- A1CF
-
Background
- Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
-
Molecular Weight
- 65.202 kDa
-
Gene ID
- 29974
-
UniProt
- Q9NQ94
Target
-