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A1CF antibody

The Rabbit Polyclonal anti-A1CF antibody has been validated for WB. It is suitable to detect A1CF in samples from Human and Mouse.
Catalog No. ABIN6291254

Quick Overview for A1CF antibody (ABIN6291254)

Target

See all A1CF Antibodies
A1CF (APOBEC1 Complementation Factor (A1CF))

Reactivity

  • 27
  • 7
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
Human, Mouse

Host

  • 26
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Rabbit

Clonality

  • 28
Polyclonal

Conjugate

  • 22
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  • 1
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  • 1
This A1CF antibody is un-conjugated

Application

  • 25
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  • 11
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  • 4
  • 2
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  • 1
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  • 1
Western Blotting (WB)
  • Purification

    Affinity purification

    Immunogen

    Recombinant Protein of human A1CF

    Isotype

    IgG
  • Application Notes

    WB 1:500 - 1:2000

    Comment

    Widely expressed with highest levels in brain, liver, pancreas, colon and spleen

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20C. Avoid freeze / thaw cycles.
  • Target

    A1CF (APOBEC1 Complementation Factor (A1CF))

    Alternative Name

    A1CF

    Background

    Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.

    Molecular Weight

    65.202 kDa

    Gene ID

    29974

    UniProt

    Q9NQ94
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