CDK11 antibody

Catalog No. ABIN6291900

This anti-CDK11 antibody is a Rabbit Polyclonal antibody detecting CDK11 in IHC. Suitable for Mouse and Rat.

Quick Overview for CDK11 antibody (ABIN6291900)

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK11 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CDK11 Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human CDK11B

Isotype: IgG

Application Details

Application Notes: IHC 1:50 - 1:200

Comment:

Expressed ubiquitously, Some evidence of isoform-specific tissue distribution

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Alternative Name: CDK11B

Background: This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.

Molecular Weight: 92.707 kDa

Gene ID: 984

UniProt: P21127

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase