ALX4 antibody

Catalog No. ABIN6292606

This Rabbit Polyclonal antibody specifically detects ALX4 in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ALX4 antibody (ABIN6292606)

Target: ALX4 (ALX Homeobox 4 (ALX4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALX4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ALX4 Antibody

Purification: Affinity purification

Immunogen: Recombinant Protein of human ALX4

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Comment:

Expression is likely to be restricted to bone, Found in parietal bone

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for ALX4

Target: ALX4 (ALX Homeobox 4 (ALX4))

Alternative Name: ALX4

Background: This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2), an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism, suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS), a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.

Molecular Weight: 44.241 kDa

Gene ID: 60529

UniProt: Q9H161